July 2009
Monthly Archive
Uncategorized31 Jul 2009 12:23 pm
Mayor of Aboriginal community knew of underage girls given contraceptive implants
Claims by the Form Opposition that doctors have given contraceptive implants to girls without their parents’ permission tease been to some bounds supported by the leader of a central Queensland Contemptuous boong community.
The Mayor of Woorabinda, Roderick Tobane says he is aware of girls as young as 12 being given contraceptives.
Roderick Tobane, says he has knowledge of six girls under 16 who have received the implants but he says their parents have acknowledged their children are sexually active and taken steps to ensure they do not become pregnant.
Opposition child safety spokeswoman Jan Stuckey says that she became aware of the practice on a visit earlier this year to two indigenous communities - Aurukun on Cape York and Woorabinda, west of Rockhampton and raised her concerns with the police.
The State Opposition claims have been denied by Queensland Health who say doctors always seek parental consent.
Dr. Linda Selvey Queensland Health’s acting chief health officer says the practice was rare but warranted in some circumstances.
Dr. Selvey says it is important that such health issues are not sensationalised because they are complex and sensitive and the decision to use to use the implants for minors was never taken lightly.
Dr. Selvey says Queensland Health uses education campaigns to inform people about the risk of unwanted pregnancies, but in some cases they had limited impact in minimising harm.
Premier Anna Bligh says if a girl is in state care, the Child Safety Department becomes involved and the authorities act in ‘loco parentis’ and make health decisions as they do if those children require surgery.
Child Safety Minister Margaret Keech says where department staff became aware of underage sex, including cases where girls had sought contraception, it was reported to police as required by law.
Ms Keech says the Department of Child Safety can only intervene if a child does not have a parent willing or able to protect them from risk or harm.
The issue has raised the ire of child safety advocates who are demanding more be done to stop underage sex.
Uncategorized31 Jul 2009 10:33 am
Brown Age Spots—Winning Tactics for Removing Them Naturally and For Good
One of the more unsightly features of getting older are brown age spots, which apace give away your age! Without resorting to drastic measures similarly to surgery, discover natural skin care ingredients that determination fade them fast and for capable.
The main cause of them, aside from genetic factors, is your exposure to the suns UV rays when you were younger. Overproduction, sometimes called hyperpigmentation of the skins brown pigment melanin is responsible for these brown age spots.
One of the most, if not the most effective natural ingredient on the market today is Extrapone Nutgrass. This is an extract from the Nutgrass root commonly found in India. A cream was originally developed from it as an anti-irritant, and only later was its lightening properties discovered! This is also why it is popular in skin whitening creams as the natural solution.
Extrapone nutgrass has now been shown in clinical trials to reduce melanin by up to 40%. Its effectiveness and safety have been backed up by well designed clinical studies. So you can be sure your age spots will gradually fade away naturally, and your skin will be healthier, smoother and there will be absolutely no harmful side effects.
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Rachel Hammond is a dedicated researcher and user of high quality natural skin care. Discover the very latest, natural and effective anti-aging skin care products Rachel recommends after extensive research.
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Uncategorized31 Jul 2009 01:12 am
Beach pollution is worst during new and full moon
A altered study of 60 beaches in Southern California suggests that water pollution varies with the lunar return, reaching the highest levels when tides are ebbing during the new and full moon. The findings could advise beachgoers and managers better assess the potential risk of swimming.
The broadcast appears in the Aug. 1 issue of the American Chemical Society’s journal Environmental Realm & Technology. ACS is the world’s largest precise intercourse.
Coastal water eminence is controlled by a number of complex woman and biological factors, including tidal cycles and seasonal rainfall. This complicatedness makes seaside water monitoring particular, with levels of bacteria in a certain area changing in just a few minutes.
For the new scrutiny, the researchers examined monitoring figures compiled for beaches throughout Southern California, keeping hunt down of tidal patterns and analyzing them with a view concentrations of enterococci — bacteria that entertain scientists to estimate the risk of illness from swimming in sea waters. “This is the largest array of beaches examined at the same shilly-shally with a view a similar pattern,” says Alexandria Boehm, Ph.D., an environmental contrive at Stanford University and lead author of the study.
She and her colleagues at the Southern California Coastal Salt water Delve into Activity institute that in the full and advanced phases of the moon, levels of enterococci were higher at the prodigious majority of the beaches studied. Boehm found that during so-called “spring tides,” when water levels vary the most between high and limited tides, a beach is twice as odds-on to be out of compliance with saturate quality standards. Spring tides are exceptionally high or low tides that take place during the complete and new moons, but deceive nothing to do with the season of the year.
The results are of immediate sound use to swimmers and careen managers similar, according to Boehm. “The general public can use the end of the moon and the tide the theatre to assess the relative imperil of illness,” she says. “It is riskier to swim during spring-degeneration tides [receding tide] compared to all other tidal conditions.”
Seaside managers can these days use tides as they currently use rainfall to assess warnings, Boehm suggests. When it rains, managers recommend that swimmers not enter the water for three days. “They could also make one think that during spring tides — and exceptionally spring-ebb tides — extravagantly supremacy is more likely to be impaired, and those who are jeopardy-averse should avoid swimming,” Boehm says.
The results might also improve managers identify quiescent sources of pollution at beaches. “Most sources of enterococci at beaches are unknown,” Boehm says. “Because we ground tidal signals in enterococci densities at beaches with no obvious point source, type storm drains and creeks, this suggests that there is a widespread tidally forced source of enterococci at beaches.”
Boehm suggests several candidates for this “mystery” source, including ground sands, decaying plant constituents and polluted groundwater. “Beach sands and wrack [piles of seaweed and animal remains that wash ashore] have been shown at freshwater beaches to harbor fecal indicator bacteria and even pathogenic bacteria,” Boehm says. “Beach managers who want to improve water quality at their beaches should investigate the capability of these sources to be contributors of enterococci to seagoing waters.”
Boehm cautions that enterococci from beach sands and wrack may not correlate with health risk the after all is said clearance as enterococci from runoff or sewage. “We just don’t know to save sure, since no one-liner has done an epidemiological read to connect benefactor illness to enterococci from non-intent sources other than runoff,” Boehm says. “We impecuniousness to do additional whip into shape to show compassion for the documentation of enterococci at all these beaches.”
The American Chemical Society is a nonprofit organization, chartered by the U.S. Congress, with an interdisciplinary membership of more than 158,000 chemists and chemical engineers. It publishes numerous well-organized journals and databases, convenes major fact-finding conferences and provides informative, science approach and speed programs in chemistry. Its main offices are in Washington, D.C., and Columbus, Ohio.
– Jason Gorss
The online understanding of the dig into paper cited in the first place was initially published June 15, 2005, on the journal’s Web site. Journalists can arrange access to this locality by sending an e-mail to newsroom@acs.org or calling the phone yourself to save this notice.
Michael Bernstein
m_bermstein@acs.org
202-872-6042
American Chemical Society
http://www.acs.org ![]()
Uncategorized29 Jul 2009 11:02 pm
Chimps Study Offers New Insight Into The Origin Of Face Recognition
Chimpanzees recognize their pals by using some of the unvarying brain regions that flog on when humans dawn on a familiar phiz, according to a relate published online on December 18th in Current Biology, a Chamber Prod quarterly. The analyse - the initial to check out brain vigour in chimpanzees after they attempt to match affiliated chimps’ faces - offers new understanding into the basis of face recognition in humans, the researchers said.
“We can learn about human origins by studying our closest relatives,” said Lisa Parr, a researcher at the Yerkes Nationalistic Primate Research Center, Emory University. “We can detect what aspects of benign cognition are really unique and which are present in other animals.”
Earlier studies had shown that chimpanzees, like humans, are adept at recognizing their peers. “We knew [from behavioral studies] that chimps and humans development faces similarly,” Parr said. “We wondered whether similar brain regions were responsible, and, after the most part, they seem to be.”
In the study, the researchers examined brain activity (as reflected by blood sugar metabolism) in five chimpanzees by using Positron Emission Tomography (PET) scans. (Parr famous that the Yerkes Federal Primate Inquire into Center is the only center of its kind to have on-site MRI, PET, and cyclotron facilities, making studies like Parr’s practicable.) The chimps were shown three faces, two of which were identical, while the third was of a bizarre chimp. Subjects were then asked to indicate the faces that matched. In other trials, the chimpanzees did the same like task with clip expertise images.
The imaging studies revealed eloquent face-selective activity in wisdom regions known to make up the distributed cortical gutsiness-processing network in humans. Help ponder showed distinct patches of operation in a region known as the fusiform gyrus - the immediate site of be opposite-discerning activity in humans - when chimps observed faces.
The researchers concluded that the brain regions that are active during facial recognition may represent part of a distributed neural system for image processing in chimpanzees, like that proposed in humans, in which the initial visual investigation of faces activates regions in the occipital and earthly lobes of the cerebral cortex (a portion of the imagination involved in memory, concentration, and perceptual awareness) followed by additional processing in the fusiform gyrus and other regions.
Parr emphasized, however, that there have been decades of scrutiny on facing processing in the one acumen. As the leading such boning up in chimpanzees, the new findings Casanova more questions than they can comeback, and cheer-up studies are underway.
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Article adapted by Medical Report Today from original cluster launch.
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The researchers include Lisa A. Parr, Yerkes Country-wide Primate Research Center, Atlanta, GA, Emory University, Atlanta, GA, Center in behalf of Behavioral Neuroscience, Atlanta, GA; Erin Hecht, Yerkes Popular Primate Research Center, Atlanta, GA, Emory University, Atlanta, GA; Sarah K. Barks, Yerkes National Primate Research Center, Atlanta, GA, Emory University, Atlanta, GA Todd M. Preuss, Yerkes Resident Primate Delve into Center, Atlanta, GA, Emory University, Atlanta, GA, Center for Behavioral Neuroscience, Atlanta, GA; and John R. Votaw, Yerkes Native Primate Exploration Center, Atlanta, GA, Emory University, Atlanta, GA.
Source: Cathleen Genova
Cell Press ![]()
Uncategorized29 Jul 2009 11:38 am
Surfing injuries - Wipin’ out wipe out
Much as surfers have their own peculiar lingo, they also incur an array of injuries from the display that can be just as peculiar to physicians, according to digging presented at the annual meeting of the Radiological Society of North America (RSNA).
When surfers are injured, many times there are no telltale abrasions since the impact is often with water and not a solid object. Surfers are also usually leashed to their boards, making it easier for them to strike the boards even after they tumble off.
“Emergency physicians need to diagnose quickly, but without an understanding of some of the unique aspects of surfing injuries, they’re apt to take additional time trying to determine what happened,” said lead author and recreational surfer Jeremy Kuniyoshi, M.D., a radiology resident at the University of California San Diego. “Most doctors know more about riding golf carts than riding waves.”
Dr. Kuniyoshi examined the radiologic images of 135 patients with surfing-related injuries and grouped them into three main causal categories, each with commonly associated injuries:
Paddling toward the surf
Catching a gesticulation
Seafaring mise en scene
Injuries associated with paddling toward waves included dislocated shoulders, as well as board traumas like skull fractures, facial fractures and bruises to the vocal chords. Common injuries suffered while catching or riding a wave included head and neck trauma, broken arms and legs, and damage to the knees. Environmental injuries included foreign matter in the lungs, damage to the ear canals from exposure to cold water, lacerations from surf board fins, and stings and bites from marine life.
“Once you hear the surfer’s story, you can see how it happened,” Dr. Kuniyoshi said. “But if you don’t hear a story and you don’t know much about surfing, the injuries really don’t make sense.”
The number of surfers in the United States increased nearly 50 percent to 2.18 million between 1987 and 2000, according to American Sports Data Superstudy of Sports Participation. Dr. Kuniyoshi, who’s been surfing for three years, contends the sport is relatively safe and hopes his research will assist physicians faced with surfing injuries.
“An understanding of the common injuries that occur during various stages of surfing can help doctors order the right radiologic exams, know exactly what to look for in the images and ultimately make quicker and perhaps more accurate diagnoses,” he said.
Co-authors of the surfing study are Mini Nutan Pathria, M.D., and David J. Smith, M.D.
http://www.rsna.org/
An internet based survey found the following:
451 surfers from 24 countries responded to the survey, and 25 (6%) were excluded. 426 individuals reported 458 acute injuries and 178 chronic injuries. Laceration (40%) was the most common acute injury followed by contusion (12%), sprain (11%), and fracture (6%). 37% of acute injuries involved the lower extremities, 35% the head and neck, 16% the trunk, and 12% the upper extremities. 55% of acute injuries resulted from contact with the surfer’s own board, 11% from another surfer’s board, and 18% from the ocean floor. Fins (40%) were the most common cause of injury from the surfer ’s own board while the nose (48%) was the most common cause from another’s board. Recoil of the surfboard on its leash occurred with 13% of all acute injuries. Shoulder strains (16%) were the most common chronic injury.
Andrew Nathanson, M.D., Philip Haynes, M.D., Ph.D. Kelly Tam Sing, M.D., and Daniel Galanis, Ph.D.
Click here to read the full survey http://www.surfstudy.sitehosting.net
Uncategorized28 Jul 2009 03:12 pm
Reducing Hospital-Acquired Infections By Using Soap-Sniffing Technology
Upbraid it a Breathalyzer for the hands.
Using sensors capable of detecting drugs in breath, new technology developed at University of Florida monitors health-care workers’ hand hygiene by detecting sanitizer or soap fumes given unlikely from their hands.
By reminding workers to clean their hands to take out virus-causing organisms such as the bacteria MRSA, the system could workers reduce polyclinic-acquired infections and redeem millions of dollars fashionable spent to treat them.
The trademarked system, called HyGreen, logs, down to the second, the frequency of hand cleaning and acquaintance with patients in a database that clinical supervisors can review this instant.
This is the prime scheme that enables real-mores monitoring of cuffs washing.
“This isn’t significant brother, this is just another tool,” said Richard J. Melker, M.D., Ph.D., a UF College of Panacea anesthesiology professor who developed the technology along with professors Donn Dennis, M.D., and Nikolaus Gravenstein, M.D., of the anesthesiology department, and Christopher Batich, Ph.D., a materials science professor in the College of Engineering. “A hospital worker not in the least wants to be guilty for someone getting sick or sinking from an infection acquired in the hospital.”
HyGreen is at the present time being tested in the Neuro Intensive Be responsible for Unit at Shands at UF medical center, and will be presented at the annual meeting of the Alliance in the direction of Professionals in Infection Control and Epidemiology June 6 to June 9 in Fort Lauderdale, Fla.
Here’s how it works: The health-care worker squirts sanitizer gel or soap into his or her indicator before passing it under a obstruction-mounted sensor. A wireless signal from a badge pooped by the worker activates a green light on the will-washing sensor. When the worker enters a patient room, a monitor near the bed detects the status of the badge, and flashes green if the personally has vacuum hands. If the living soul has not washed, or too much obsolete has passed between washing and approaching the patient, the badge intention give a soft “reminder” vibration.
“I do wash my hands more often,” said wet-nurse Carrie McGirr, R.N., who volunteered to help try out the HyGreen system. “It’s a fairly four-square process to learn.”
Unite to 2 million sanitarium-acquired infections occur each year and more than 250 related deaths occur each day in the United States, according to the Centers for Bug Mechanism and Slowing.
“A substantial horde of those are preventable, and also a woman of the key modes of transmission is via the hands of vigour-carefulness personnel and patients,” said Dr. Lennox Archibald, a professor of transmissible diseases at the UF College of Drug, and the Shands at UF epidemiologist leading the evaluation of HyGreen.
Six pathogens, including the ones known as MRSA and VRE, account for two-thirds of all hospital-acquired infections and are willingly transmitted by index.
Studies have shown that up to half of all hospital-acquired infections might be prevented if health-care workers washed their hands according to guidelines enhance forth by the CDC.
It costs at least $30 billion a year in additional spending to present sanatorium-acquired infections. The Center after Medicare and Medicaid Services last year ruled that it would no longer compensate hospitals in favour of the expense of treating the infections.
Today, more than 160 years after Hungarian physician Ignaz Semmelweiss was ridiculed against suggesting that share washing by doctors who moved directly from working with cadavers to delivering babies could reduce fatal cases of blood-correlated infection, the practice motionless meets with resistance.
“But it’s not because people don’t appetite to do it,” Archibald said. “It’s not indigenous in people’s behavior to wash their hands, for some as a result of.”
Divers studies screen that salubriousness-care workers wash their hands less than half the time after direct touch with patients. The reasons people give include skin irritation caused by hand hygiene products, a preference because gloves or simply failure to bear in mind.
Previous management-washing compliance studies have been based on surveillance of a limited number of people at a time, who likely improve their behavior when they know they are being watched - a phenomenon known as the Hawthorne effect.
“This system is a noninvasive motion of measuring - it allows in requital for nonbiased elapsed time and is reserved,” said Loretta Fauerbach, Shands at UF director of infection control, who helped write the CDC hand-washing guidelines and leads the collaboration with HyGreen to evaluate the way in a hospital setting.
“Nobody has ever taken a systems approach to this problem to come,” said Melker, chief technology officer of Xhale Inc., which is marketing HyGreen.
Developers anticipate that hospitals inclination readily accept the system because not single can it help reduce infections, it also force takings for itself within a only one months.
“Something has to be done about deal out washing,” Archibald said. “Otherwise the bugs are going to succeed in.”
Source:
Czerne M. Reid
University of Florida ![]()
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Uncategorized26 Jul 2009 02:38 pm
Court rules in favor of Sandoz on Toprol Xl patent
Sandoz was pleased to learn this week that the U.S. Court of Appeals in St. Louis has affirmed a summary judgment by U.S. District Judge Rodney Sippel invalidating patent shelter on Toprol XL, a beta blocker hand-me-down to probe angina, essence failure, and boisterous blood pressure.
Recent Articles on Medical: Impotencia remedios.
Sandoz introduced metoprolol succinate 25 mg extended release tablets, a generic equivalent of Toprol XL, in the U.S. late last year. Sandoz announced this past May that the U.S. Food and Drug Administration granted final approval to its abbreviated new drug application for metoprolol succinate 50 mg ER.
Sandoz, a division of the Novartis group, is a global leader in the field of generic pharmaceuticals, offering a wide array of high-quality, affordable products that are no longer protected by patents. Sandoz has a portfolio of more than 840 compounds in over 5,000 forms worldwide and sells its products in more than 110 countries. Key product groups include antibiotics, treatments for central nervous system disorders, gastrointestinal medicines, cardiovascular treatments and hormone therapies. Sandoz develops, produces and markets these drugs along with pharmaceutical and biotechnological active substances and anti-infectives. In addition to the strong organic growth in recent years, Sandoz has made a series of acquisitions including Lek (Slovenia), Sabex (Canada), Hexal (Germany) and Eon Labs (U.S.). In 2006, Sandoz employed approximately 21,000 people worldwide and posted sales of USD 6 billion.
http://www.sandoz.com/
Uncategorized25 Jul 2009 10:28 am
Wake-Up Call To Women To Do More To Prevent Cancer
When it comes to preventing cancer, women think they’re doing more than they in point of fact are. It is possible that most surprising, women are more afraid of getting Alzheimer’s disease than cancer, even though cancer causes almost ten times more deaths per year.
These are among the new findings of a national estimation record by The University of Texas M. D. Anderson Cancer Center and Prevention of 800 women between the ages of 18 and 93. The examine, partial of a November deliver special feature, “Winning the War on Cancer,” hits newsstands this week.
Less than an individual third of respondents said they are putting % into usage what science has shown moving toward preventing cancer, including following routine recommended guidelines for fit eating and execution. More alarming, fro 42 percent of women who responded said they felt little or no sense of control over cancer and numberless aren’t doing much to thwart the disease, when in fact, 63 percent of cancers are caused by labile behaviors: smoking, poor diet, man idleness and portliness.
Cancer will evince dreadful suitable an estimated 270,000 women in 2007, with the greatest number of cancer deaths attributed to lung cancer. Generally 678,000 new cases of cancer in women will be diagnosed in the United States this year, including over 178,000 new cases of tit cancer1. Looking at these statistics, the M. D. Anderson-Prevention poll sought to gauge women’s adeptness, fears and sense of control through cancer; what, if anything, they are doing to dodge the ailment and how these efforts evaluate up to recommended guidelines.
According to the poll, women who rated themselves as higher on the social rank ladder — regardless of store — and who reported a stronger support network, were more plausible to disgrace a accommodate an activist approach to personal health and endure empowered in their ability to lower their cancer risk. In differ, women who viewed themselves as being of diminish collective status in their communities were less conceivable to engage in behaviors that are known to decrease cancer risk. In fact, they were more liable to to be smokers and less likely to father ever had a mammogram.
The poll found that women who smoke — a behavior that is extremely detrimental in its own accurate — are also more likely to engage in a constellation of other unhealthy behaviors. Women smokers rated their haleness as significantly poorer than non-smoking respondents. Although they admitted they know their cancer risk is “moderate to identical important,” they are still less liable to snack without delay, exercise or to have had a mammogram.
“Our findings about to break down complex subconscious, common and behavioral components behind health decisions women confirm to avoid cancer. Interestingly, we catch a glimpse of that women who feel cognate with they have more control over with cancer are more apt to enroll in healthy behaviors, and as a result, do take more control. Payment women, one influence say cancer block is a status of mind,” according to the survey’s lead author, Jennifer Irvin Vidrine, Ph.D., collaborator professor, Sphere of influence of Health Disparities Probing at M. D. Anderson, and an experienced on cancer form disparities.
A gap between knowing and doing in terms of recommended guidelines The majority of women say they eat a healthy diet (81 percent) and performance regularly (73 percent), but:
* only 31 percent squander the recommended diurnal fruit servings (2/day)
* as few as 12 percent probe getting enough vegetables (3/day)
* only 32 percent actually cross 150 minutes of drill per week, the minimum recommended for cancer arrest
When it comes to cancer screenings, there’s room to improve:
* 67 percent of respondents majority 40 and older have had a mammogram within the done 12 months
* 77 percent have had a Pap test within the past three years
* but at worst 57 percent of respondents stage 50 and older have been screened into colon cancer (colonoscopy or sigmoidoscopy)
* of smokers, 65 percent had ever had a mammogram; and 23 percent entertain had a sigmoidoscopy or colonoscopy
On the brand-new HPV vaccine — which protects against cervical cancer — through despite girls and women ages 9 to 26:
* 67 percent of respondents had heard about it
* 78 percent of those who had heard of it small amount that girls in the age group should receive it, and
* 70 percent of women with daughters under the age of 26 (one third of respondents) who had heard of the vaccine wanted their daughter to seize it
Controlling rewrite man-in-chief Liz Vaccariello says, “We be informed that all cancers caused by cigarettes can be prevented and that a host of others - caused by corpulence, inactivity, nutrition, catching agents and the sun’s rays - can be avoided or successfully treated when detected early. The poll begins to tap into discrepancies between what people think they are doing to protect their salubriousness and what they are actually doing, and areas where overall knowledge could be improved.”
Dr. Irvin Vidrine says the findings underscore how obscure it is to change personal behaviors, particularly for women whose family and career responsibilities may leave little time to tend to personal strength matters. “Our findings should upon as a wake-up call to women. As the divide between knowing and doing becomes clear, women can be more circumspect in compelling their cancer prevention behaviors to a higher level of compliance.”
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Article adapted by Medical News Today from inventive press release.
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The M. D. Anderson-Prevention horn vote was conducted by Gelb Consulting in May 2007; details can be set at http://www.mdanderson.org/ and http://www.delay.com/cancer.
About M. D. Anderson Cancer Center: M. D. Anderson Cancer Center, an institution created by the Texas Legislature in 1941, has established an international noted as one of the world’s preeminent centers for cancer patient care, research, education and prevention. A multidisciplinary approach, and dedication to translational research, schooling and prevention are hallmarks of M. D. Anderson. Looking to the future, M. D. Anderson is increasingly focused on sharing new inspect developments and clinical expertise through affiliations with head institutions roughly the world. M. D. Anderson was designated by the National Cancer Institute (NCI) as one of the in the first place three Comprehensive Cancer Centers in the United States. In 2007, U.S. Expose & Faction Report’s “America’s In the most suitable way Hospitals” inquiry ranked M. D. Anderson as the supreme hospital in the state for cancer care, the fifth time in eight years that the institution has achieved the highest ranking. M. D. Anderson has provided care for more than 700,000 cancer patients since 1944 and 74,000 in the last year unescorted.
About Prevention: Frustrating is the #1 healthy lifestyle publication manufacturer and the 10th largest magazine in the polity, with not quite 11 million readers. The best online salubrity armoury end, Hampering.com has 1.6 million sui generis visitors each month. This year, Prevention last will and testament publish more than 15 branded books, 18 red-letter-interest publications, 14 international editions, five bookazines and five DVDs under the bestselling Thwarting Wholesomeness Systems. Team Prevention, http://www.prevention.com/walking, also will moving walking events at five marathons across the native land this year.
Conjunction:
Robyn Stein
Gabbegroup
Karen Mazzotta
Preventing
Source: Robin Davidson
M. D. Anderson Cancer Center ![]()
Uncategorized22 Jul 2009 08:23 am
Aethlon Medical Reports Promising Treatment Results In Hepatitis-C Infected Patients
Aethlon Medical, Inc. (OTCBB:AEMD) announced preliminary matter of Hepatitis-C (HCV) infected patients treated with the Aethlon Hemopurifier®, a medical device designed to assist the immune response in combating infectious disease. The HCV treated patients were supply end-stage renal sickness (kidney dialysis) patients enrolled in vulnerable safety studies being conducted at the Fortis Health centre, in Delhi, India.
In the studies, in fine viral weight reductions were observed in tested patients completing a three-treatment Hemopurifier® protocol. The resulting facts documented that two of three HCV patients tested responded with measurable viral responsibility reductions during the course of three 4-hour Hemopurifier® treatments. The three treatments were administered during scheduled dialysis therapy every other day onto the span of five days. The third patient showed both increases and decreases in viral load during the course of treatment, but demonstrated an overall reduction in follow-on viral cargo tests. Given the peewee illustrative size, viral responsibility text was averaged quest of all 3 patients. Average initial HCV viral load was 3.13 x 108 viral units per ml of blood. After completion of three Hemopurifier® treatments, viral load was reduced an usual 57% (final 4.1×107 IU/ml). The stepwise trickle in HCV viral load averaged 36% per treatment. Follow-on testing indicated that HCV viral stuff was 60% lower than beginning viral load values when measured three days after final Hemopurifier® treatment, and at seven days post treatment, viral load declined to 82% unworthy of starting viral load values. Additionally, not any of the patients were being treated with antiviral drug therapy. Viral load measurements were performed with real-meanwhile quantitative polymerase chain reaction (RT-PCR). Control samples were predetermined in duplicate while treatment samples were generally careful in triplicate. In conclusion, the Hemopurifier® treatment of HCV infected patients undergoing dialysis resulted in a net viral pack reduction of 60 to 80% with the effects of treatment progressing at least 7 days beyond Hemopurifier® treatment.
“The pronouncement of progressive viral onus reduction after only three Hemopurifier® treatments suggests that extended Hemopurifier® treatment applications could effectively repress disease spreading in HCV patients,” stated Aethlon Chairman and CEO, James A. Joyce. “We rarely plan to advance explain a rapid virological response (RVR) through a box study of an HCV unaggressive receiving up to four weeks of Hemopurifier® analysis.” Studies have shown that hurried virological response (RVR) at week four is a strong predictor of sustained virological response (SVR) in HCV patients. SVR is defined as undetectable viral load for a littlest stretch of five months after conclusion of treatment.
The opportunity for novel antiviral strategies to bicker HCV is notable, as approximately 180 million people worldwide (3% of the world’s population) are HCV infected. According to the Overjoyed Health Organization (WHO), at most 30-50% of infected patients beneficially commiserate with to the 48-week pegylated interferon-ribavirin treatment principle.
The Hemopurifier® is a first-in-class medical mark of cadency designed to assist the invulnerable response in combating infectious disease by rapidly clearing viruses and immunosuppressive proteins from circulation. The gambit provides a novel identity theory to crew antiviral therapies by suppressing the emergence of viral strains that cause drug resistance. The Hemopurifier® is also positioned to fill the unmet clinical need of treating patients resistant to medication psychoanalysis or infected by viral pathogens that are untreatable with drug and vaccine therapy. In HCV care, the device is positioned as an adjunct to enhance clinical outcomes of the pegylated interferon-ribavirin treatment standard. Other opportunities in HCV mind a look after include the treatment of individuals who sink or are not able to endure prevailing of care analysis, tip-stage renal patients infected with HCV, and HIV patients co-infected with HCV.
About Aethlon Medical
Aethlon Medical is the developer of the Hemopurifier®, a basic-in-pedigree medical device designed to treat contagious disease. The Hemopurifier® provides real-loiter again and again therapeutic filtration of catching viruses and immunosuppressive particles, and is positioned to address the treatment of upper and vaccine unsubmissive viruses. Additionally, the device holds promise in cancer be fond of, as experiment with studies have verified the Hemopurifier® is able to capture immunosuppressive particles secreted by tumors. The Hemopurifier® is designed to act both as a stand-alone therapeutic, and as an adjunct treatment to boost clinical benefit of established therapies. Pre-clinical studies conducted by researchers representing pre-eminent government and non-government health organizations both in the United States and abroad have documented the effectiveness of the Hemopurifier® in capturing from flow the viruses that constitute pandemic threats, including H5N1 Avian Influenza (bird flu), and Dengue Hemorrhagic Fever (DHF) from circulation. The band is conducting studies to support the use of the Hemopurifier® as a broad-spectrum treatment countermeasure against bioterror threats, including Smallpox, and Ebola, Marburg, and Lassa hemorrhagic fever. Regulatory and commercialization initiatives in the United States are presently focused on bioterror threats, while international initiatives are directed toward naturally evolving pandemic threats, and chronic contagious affliction conditions including the Benignant Immunodeficiency Virus (HIV) and Hepatitis-C (HCV). Aethlon demonstrated the sanctuary of the Hemopurifier® in a 24-treatment forgiving ruminate on at the Apollo Hospital in Delhi, India, and is currently conducting aid human studies at the Fortis Hospital, also located in Delhi. The entourage has submitted an investigational machine impunity (IDE) to the U.S. Food and Drug Delivery (FDA) to move up the Hemopurifier® as a broad-spectrum treatment countermeasure against category “A” bioterror threats. Additional poop regarding Aethlon Medical and its Hemopurifier® technology is on tap online at http://www.aethlonmedical.com.
Certain of the statements herein may be forward-looking and involve risks and uncertainties. Such forward-looking statements involve assumptions, known and unknown risks, uncertainties and other factors which may cause the genuine results, act or achievements of Aethlon Medical, Inc to be significantly new from any future results, performance, or achievements expressed or implied by the support-looking statements. Such potential risks and uncertainties include, without limitation, the Company’s adeptness to raise initial when needed, the Company’s ability to round out the development of its planned products, the ability of the Following to obtain FDA and other regulatory approvals permitting the sale of its products, the Company’s gift to manufacture its products and accommodate its services, the impression of government regulations, patent protection on the Company’s proprietary technology, product barrier endangerment, uncertainty of market acceptance, championship, technological change, and other risk factors. In such instances, actual results could differ materially as a sequel of a mix of factors, including the risks associated with the tenor of changing economic conditions and other risk factors detailed in the Company’s Securities and Exchange Commission filings.
Aethlon Medical, Inc. ![]()
Uncategorized21 Jul 2009 01:44 am
How The Body Recognizes A Fungus Among Us
The fungus Candida albicans can cause a wide classification of infections, ranging from mucosal infections in unspecifically healthy individuals to sentience-threatening infections in persons with impaired immunity. Beating this infection requires mononuclear immune cells such as neutrophils and macrophages to endorse the fungus, ingest it, and kill it by releasing proinflammatory cytokines that activate the immune response. In a turn over appearing online on May 18 in advance of print flyer in the June uncertain of the Journal of Clinical Investigation, Mihai Netea and colleagues from Radboud University Nijmegen Medical Center, The Netherlands, show how mononuclear cells salute the cell surface of C. albicans. They reveal that this handle involves multiple perception systems that distinguish various components within the layers of the fungal cell wall.
The authors examined mutant strains of C. albicans that had specified defects in the mannosylation of chamber lose everything proteins. They demonstrated that 3 components of the fungal stall wall are involved in the recognition by monocytes/macrophages and fit the resulting activation of proinflammatory cytokine release: (i) N-linked mannans; (ii) O-linked mannans; and (iii) beta-glucans. The N-linked and O-linked mannosyl groups of glycoproteins of the outer emerge of the cell protection were to blame for most of the cytokine-stimulating activity of the fungal cubicle. This was achieved by clear-cut interaction of the N-linked mannosyl residues with the mannose receptor, and of the O-linked mannosyl residues with Fee-like receptor 4. Residual cytokine stage was mediated by beta-glucans interacting with a protein called dectin-1, and most plausible in cooperation with Toll-like receptor 2. This study whim serve as a model for time to come studies of how the immune system recognizes other microorganisms.
TITLE: Safe sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors
View the PDF of this article at:
the-jci.org/article.php?id=27114
Brooke Grindlinger
press_releases@the-jci.org
Yearbook of Clinical Investigation
http://www.jci.org ![]()
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